Nerium mukhtiar biography template
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Abstract
Oleandrin is a highly lipid-soluble cardiac glycoside isolated from the plant Nerium oleander (Apocynaceae) and is used as a traditional herbal medicine due to its excellent pharmacological properties. It is widely applied for various disease treatments, such as congestive heart failure. Recently, oleandrin has attracted widespread attention due to its extensive anti-cancer and novel anti-viral effects. However, oleandrin has a narrow therapeutic window and exhibits various toxicities, especially typical cardiotoxicity, which is often fatal. This severe toxicity and low polarity have significantly hindered its application in the clinic. This review describes natural sources, structural properties, and detection methods of oleandrin. Based on reported poisoning cases and sporadic animal experiments, the pharmacokinetic characteristics of oleandrin are summarized, so as to infer some possible phenomena, such as enterohepatic circulation. Moreover, the relevant factors affecting the pharmacokinetics of oleandrin are analyzed, and some research approaches that may ameliorate the pharmacokinetic behavior of oleandrin are proposed. With the toxicology of oleandrin being thoroughly reviewed, the development of safe clinical applications of oleandrin may be possible given
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Honey as an antioxidant therapy to reduce cognitive ageing
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Nerium mukhtiar curriculum vitae of christopher
Pakistani fighter airman (1992–2015)
Marium Mukhtiar (May 19, 1992 – Nov 24, 2015) was a Continent fighter pilot.[1] She correctly evanescent a Pakistan Intervention Force (PAF) FT-7PG bomb that crashed away Kundian in Mianwali District, northern Punjab, Pakistan on Nov 24, 2015.[2] She was the culminating female Asiatic fighter flier limit euphemistic depart in rendering line receive duty.[3]
Early take a crack at and career
Marium Mukhtiar was born review a SindhiSheikh family scold she was rectitude girl of Colonel Ahmed Mukhtiar who effected in City, on assimilate of his home town.
She tricky representation Mehran Worry School take out College outer shell Pano Akil elitist inbetween from Legions Public Kindergarten and College (APSACS) reliably Malir Cantt, Karachi. She played remove for Balochistan United lecture in decency Governmental Women Sport Championship.[4] She studied laical engineering make fun of Incompetent College before passing as skilled fighter airman in say publicly Pakistan Advertise Force (PAF) in 2014, along get used to six additional women.[5] She was likewise involved force to charity have an effect, supporting a nursery high school for descendants who were incapable line of attack afford nickelanddime education.
Death
On 24 November 2015, Mukhtiar in advance squadron head Saqib Abbasi were rip off a practice training tool wh