Leloir luis federico biography of williams
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Nobel Prize in Chemistry for his discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates.
Department of Biochemistry Postdoctoral Researcher ().
Luis Federico Leloir was remarkable even within the ranks of Nobel Prize-winning scientists, most of whom have been honoured for identifying a specific agent or pathway, or for defining a structure or principle. Leloir, however, discovered a completely new class of biological compounds. These are hybrids of nucleotides and sugars that facilitate the synthesis of oligo- and poly-saccharides in all living organisms. For this he received the Nobel Prize in Chemistry, thereby becoming only the second Argentinian Nobel Laureate in science.
Leloir was born in Paris but his Argentinian parents returned to their homeland when he was two years old. This led to him graduating in medicine from the University of Buenos Aires in and going on to take a PhD under the supervision of the endocrinologist Bernardo Houssay, whose work led to him sharing the Nobel Prize in Medicine with Carl and Gerty Cori.
Aware that his grasp of biochemistry was inadequate for the direction in which his scientific curiosity was taking him, Leloir then spent a year in the Biochemical Laboratory in Cambridge under the overall direction of Fr
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Luis Federico Leloir
Argentine physician beginning biochemist (–)
"Leloir" redirects field. For badger uses, depiction Leloir.
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Biography
[edit]Early years
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Leloir, Luis Federico
(b. Paris, France, 6 September ; d. Buenos Aires, Argentina, 2 December ),
biochemistry, nucleotide sugars, oligoand polysaccharide synthesis.
Leloir received the Nobel Prize in Chemistry for his discovery of nucleotide sugars and the role of those compounds in the interconversion of monosaccharides and as precursors in the synthesis of oligo- and polysaccharides. His many contributions to biochemistry also include the first description of fatty acid oxidation in a cell-free system, of angiotensinogen and its conversion to angiotensin upon incubation with rennin, and the role of lipid-bound saccharides as intermediates in protein glycosylation.
Medical and Biochemical Training . Luis F. Leloir was born in Paris, France. His Argentine parents had traveled to the French capital seeking medical treatment for the father, a lawyer who never practiced his trade. Two years later his mother (his father died before Leloir’s birth) took him to Buenos Aires. He studied medicine at the University of Buenos Aires, becoming a medical doctor in From – he was an internist at the University Hospital while doing the experimental work for his doctoral thesis under the supervision of Bernardo A. Houssay. Houssay was director of the Institute of Physiology of the