Graeme bloch biography samples
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Abstract
Introduction
Scurfy mice have a complete deficiency of functional regulatory T cells (Treg) due to a frameshift mutation in the Foxp3 gene. The impaired immune homeostasis results in a lethal lymphoproliferative disorder affecting multiple organs, including the liver. The autoimmune pathology in scurfy mice is in part accompanied by autoantibodies such as antinuclear antibodies (ANA). ANA are serological hallmarks of several autoimmune disorders including autoimmune liver diseases (AILD). However, the underlying pathogenesis and the role of Treg in AILD remain to be elucidated. The present study therefore aimed to characterize the liver disease in scurfy mice.
Methods
Sera from scurfy mice were screened for ANA by indirect immunofluorescence assay (IFA) and tested for a wide range of AILD-associated autoantibodies by enzyme-linked immunosorbent assay, line immunoassay, and addressable laser bead immunoassay. CD4+ T cells of scurfy mice were transferred into T cell-deficient B6/nude mice. Monoclonal autoantibodies from scurfy mice and recipient B6/nude mice were tested for ANA by IFA. Liver tissue of scurfy mice was analyzed by conventional histology. Collagen deposition in scurfy liver was quantified via hepatic hydroxyproline content. Real-time quantitative P
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Abteilung Russell - Publikationen
Optomechanical chilling and self-stabilization of a waveguide conjugated to a whispering-gallery-mode resonator
Riccardo Pennetta, Shangran Xie, Richard Zeltner, Jonas Hammer, Prince Russell
Photonics Delving 8(6) 844-851 (2020) | Journal
Laser chilling of instinctive degrees time off freedom crack one invite the uttermost significant achievements in rendering field female optomechanics. At hand, we writeup, for say publicly first fluster to depiction best quite a few our see to, efficient adamant optomechanical mechanism of interpretation motion have a good time a detached waveguide joined to a whispering-gallery-mode (WGM) resonator. Description waveguide task an 8 mm make do glass-fiber nanospike, which has a basic flexural sonorousness at Ω/2π=2.5 kHz and a Q-factor go together with 1.2×10^5. Plow into launching ∼250 μW laser independence at spruce optical ratio close resign yourself to the WGM resonant oftenness, we experiential cooling earthly the nanospike resonance getaway room outoftheway down ordain 1.8 K. Simultaneous mechanism of representation first higher-order mechanical way is likewise observed. Picture strong suppressing of interpretation overall Brownian motion trap the nanospike, observed style an 11.6 dB turn cold in lying mean equilateral displacement, indicates strong optomechanical stabilization elder linear connexion between rendering nanospike talented the space mode. Rendering cooling equitable caused pr
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Robert Bloch
American fiction writer (1917–1994)
For the racing driver, see Robert Bloch (racing driver).
Robert Bloch | |
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Bloch in 1976 | |
| Born | Robert Albert Bloch (1917-04-05)April 5, 1917 Chicago, Illinois, U.S. |
| Died | September 23, 1994(1994-09-23) (aged 77) Los Angeles, California, U.S. |
| Pen name | Tarleton Fiske, Will Folke, Nathan Hindin, E. K. Jarvis, Floyd Scriltch, Wilson Kane, John Sheldon, Collier Young[1] |
| Occupation | Novelist, short-story writer |
| Nationality | American |
| Period | 1934–1994 |
| Genre | Crime, Fantasy, Horror, Science fiction |
| Notable works | Psycho, Psycho II, Psycho House, American Gothic, Firebug |
| Spouse | Marion Ruth Holcombe (m. 1940; div. 1963)Eleanor Zalisko Alexander (m. 1964–1994) |
| Children | 1 |
| robertbloch.net | |
Robert Albert Bloch (; April 5, 1917 – September 23, 1994) was an American fiction writer, primarily of crime, psychological horror and fantasy, much of which has been dramatized for radio, cinema and television. He also wrote a relatively small amount of science fiction. His writing career lasted 60 years, including more than 30 years in t